Journal: EJNMMI Radiopharmacy and Chemistry

Article Title: Evaluation of polydentate picolinic acid chelating ligands and an α-melanocyte-stimulating hormone derivative for targeted alpha therapy using ISOL-produced 225 Ac

doi: 10.1186/s41181-019-0072-5

Figure Lengend Snippet: 225 Ra/ 225 Ac radiochemical separation method used for purification of ISOL-produced 225 Ac. The solution resulting from etching 225 Ra and 225 Ac from the aluminum target was diluted with nitric acid (to 4 M HNO 3 ) and loaded onto a preconditioned DGA resin (Horwitz et al. ). After washing the resin (with 4 M HNO 3 ) to remove residual 225 Ra II , the 225 Ac III was eluted from the resin 0.5 mL of 0.05 M HNO 3

Article Snippet: Branched DGA resin ( N,N,N′,N′ -tetrakis-2-ethylhexyldiglycolamide, 50–100 μm particle size) was purchase from Eichrom Technologies (Lisle, IL, USA).

Techniques: Purification, Produced

Journal: ACS Central Science

Article Title: Synthesis and Characterization of the Actinium Aquo Ion

doi: 10.1021/acscentsci.6b00356

Figure Lengend Snippet: Elution profile of 225 Ra, 225 Ac, and 173 Lu separations using DGA (Eichrom) on a Bio-Rad column (1 mL of resin in 10 mL column).

Article Snippet: This effluent was diluted with water so that the final HNO 3 concentration was 6 M. This Ac III containing solution was then loaded onto a second Biorad column (10 mL) containing a DGA (1 mL; Eichrom) resin that had been conditioned with H 2 O (3 × 10 mL) followed by HNO 3 (1 × 10 mL; 6 M).

Techniques: